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Osteogenic Loading Validation

Multiple-of-bodyweight axial bone loading using novel exercise intervention with and without bisphosphonate use for osteogenic adaptation

J. Jaquish

Performance Health Systems, Chicago, United States

Received 4 August 2013; revised 8 August 2013; accepted 9 September 2013


Aim: To determine bone density adaptation from multiple-of- bodyweight (MOB) compressive force with exercise apparatus designed for osteogenic loading.
Methods: Osteogenic Loading (OL) apparatus was used to isolate optimal ranges of motion allowing for axial bone loading at levels that could be MOB (force/loading measured by load cells within the OL apparatus). Optimal positions for OL were verified by analysis of force production maximization [1]. Volunteer subjects, mean age of 62.5(+/-8.2 SD), (n=14) performed 4 specific multi-joint movements on the OL apparatus, each lasting 5 seconds. Sessions were repeated once per week.

Results: Mean peak force/loading for subjects was 9.18(+/-2.63 SD) MOB (hip/legs) and 3.13(+/-0.79 SD) MOB (spine). Since different hospitals and radiology offices were used to gather DXA data, not all subjects had both hip and spine T-scores, and weeks/sessions of using OL were not uniform, the results are presented in a case report format, depicting pre and post DXA of hip and spine. Conclusions: This MOB level of axial force has been seen to improve BMD [2, 3, 4], however has been commonly affiliated with injury. BMD improvement outcomes were observed in all subjects for one or both test sites with no instances of injury or discomfort, at levels of MOB reaching 9.18(+/-2.63 SD) MOB (hip/legs) and 3.13 (+/-0.79 SD) MOB (spine). These results suggest a larger more controlled study be done to further examine the OL stimulus and adaptation.

Jaquish, J. (2013). Multiple-of-bodyweight axial bone loading using novel exercise intervention with and without bisphosphonate use for osteogenic adaptation. Osteoporosis International. 198; 24(4), s594-s595.